Bone quality and bone microenvironment in bone disease and animal models - QOSMOS
Director - Doctor Eric AGUADO
Contact : eric.aguado(at)oniris-nantes.fr
Key words
Bone remodeling / Human bone diseases / Animal models / Biomaterials
Research thematics
Bone quality
- Analysis in man
- Pharmacological agent-treated osteoporosis
- Other minor bone diseases
- Malignant bone diseases (in case of breast and prostate cancer metastatis)
- Microarchitecture of cortical bone
- Analysis in animals
- Role of porosity on bone quality
- Role of muscular insertions on bone quality
- Analysis on biomaterials
- Quality of newly-formed bone around functionalized implants
- Implants influence
Bone microenvironment
- Analysis in man
- Bone remodeling dysregulations (during mastocytosis, myeloma, B-cells malignancies)
- Immunohistochemical analysis of bone metastasis
- Analysis in animals
- Evaluation of new drugs acting on the cytokine networks of the bone remodeling
- Analysis on biomaterials
- Artificial microenvironments to analyze tumor cells migration
- Autograft
- Non-resorbable polymers
- Calcium-phosphate materials